Cancer patients have been left free of the disease after being treated with a new drug which harnesses the power of their own immune cells.
Four of 38 patients with non-Hodgkin's lymphoma have seen the disease complete regressions following treatment, while five others saw reductions of 50 per cent in their tumours.
While the trials were only carried out on patients with blood cancer, it is hoped the methods can be adapted to tackle other cancers
The drug, which could prove cheaper than other therapies that try to achieve the same effect with cells, works by activating the body's own defences to attack the cancer.
The results have been described as an "exciting" and "significant" development in the use of immunotherapy, the process of using the body's own immune system to fight disease.
While the trials were only carried out on patients with the blood cancer, it is hoped the methods can be adapated to tackle other cancers...
...Earlier this year doctors announced that a patient with advanced skin cancer was free of the disease two years after they injected him with billions of his own immune cells using a different method. However, experts warned at the time that the process could prove extremely expensive.
The development of the drug could prove a much cheaper alternative way of providing immunotherapy treatments.
The treatment works like a vaccine and could be available within five years. Cells would be taken from the body, altered, and injected back into the affected joint.
A team at Newcastle University will now test the vaccine on volunteers with the disease...
...The vaccine works by reprogramming the body's own immune cells.
Using chemicals, steroids and Vitamin D, the team has devised a way to manipulate a patient's white blood cells so they surpress, rather than activate, the immune system.
It is thought the cells will then act as a brake on the over-reacting immune system and stop it attacking its own joints.
Although a similar technique has been used in cancer research, this is the first time it has been adapted to rheumatoid arthritis.
Prof Silman said the treatment may prove expensive as each patient would have to have their own cells taken and manipulated rather than a drug which can be made in bulk and prescribed to all people with a condition.
He said it would be unlikely that the vaccine could be offered in normal local hospitals because of the expertise necessary to manipulate the cells in the laboratory.
Researchers have announced that very early studies of the seizure medication valproic acid indicate the medication may help "flush out" HIV from remote areas in the body that are difficult to reach with conventional therapies. The very small trial combined conventional HIV medications with the seizure medication valproic acid.
For years, scientists have tried without success to attack the HIV hidden deep in the DNA of human cells. This latent (not presently active) HIV lays in wait for an opportunity to multiply and flourish, usually in the absence of effective HIV treatment. Scientist theorize that if they could eliminate this collection of latent HIV, the possibly then exists that HIV could be totally cleared from the body. Simply put, scientists believe if the latent HIV can be attacked, the potential for a cure is greatly increased.
A woman who has never shown symptoms of infection with the AIDS virus may hold the secret to defeating the virus, U.S. researchers said on Tuesday.
Infected at least 10 years ago by her husband, the woman is able somehow to naturally control the deadly and incurable virus -- even though her husband must take cocktails of strong HIV drugs to control his.
She is a so-called "elite suppressor," and studies of her immune cells have begun to offer clues to how her body does it, the team at Johns Hopkins University in Baltimore said.
"This is the best evidence to date that elite suppressors can have fully pathogenic virus," said Dr. Joel Blankson, who led the study...
... Both the man and the woman, who are from Baltimore, were diagnosed 10 years ago, Blankson said. The husband is a former injecting drug user.
Tests showed that immune cells known as CD8 T-cells from the wife stalled HIV replication by as much as 90 percent, while the husband's T-cells stopped it by only 30 percent, Blankson's team reported in the Journal of Virology.
Her virus has also mutated in apparent response to this immune attack, becoming weaker, while her husband's virus has remained strong.
"Elite suppression offers clues to vaccine researchers on many fronts: how CD8 killer T-cells can attack HIV and how a stronger immune response can force HIV into a permanent defensive state," Blankson said.
"We are trying to figure out exactly how the T-cells work in her to inhibit viral replication," he added. "We are just trying to see what kind of cytokines they make."
According to Chinese authorities, preliminary tests of its first AIDS vaccine indicate it could protect people against the HIV virus.
The State Food and Drug Administration says of the 49 healthy men and women, aged 18-50 who took part in a first phase trial, none experienced severe adverse reactions.
The participants were divided into eight groups and were sampled 5 to 10 times during the 180-day period of the trial after taking both low and high dosages.
The researchers say they showed a reasonably positive immune response towards the virus, and the higher the dosage, the better their reaction.
The group also received DNA fragments of HIV-1 and according to the research team, some developed immunity to HIV-1 two weeks after being vaccinated; this they believe indicates that the vaccine stimulates the immune system.
The researchers are still analysing the trial results before making a decision on whether further tests should be carried out.
The vaccine has been tested on children in Africa who died and is being tested on children in the U.S. right now. The fate of other "volunteers" is not known, having been kept as a virtual state secret by the health establishment.
Quote by TriSec:
One more thing from KO[Maddow] last night....the number of Republicans who have suddenly had "schedule conflicts" with the Convention...
On the list is Maine's senator Susan Collins. I did my homework on her when we were investigating moving to Maine....she's one of the good ones, a real old-school Republican. She has teamed up with our own Senator Kennedy on many pieces of legislation relevant to New England...so I'd count her as a "friendly", or at least someone we can work with.
Quote by TriSec:
Being the underdog is fine, unless we're talking Rotweiller-on-Miniature Schnauzer action...
Quote by TriSec:
Ah Random, it's being diplomatic.
"Schedule Conflict" is code for "I don't want to be seen with that fuck!"
It actually makes me think more highly of those not going; perhaps there is a shred of integrity and decency under there somewhere.
Of course for some of them, it's opportunistic; I'd wonder how many of them are up for re-election in a closely contested district, and they can't afford taking a risky ride on a coattail?
"Sudan's Big Men have excelled in their peculiar environment by mastering two intertwined requirements of power. The first is the art of manipulating potent symbols, masking one's personal agenda in a larger legitimating cause. It must be a cause which justifies extreme measures, and for which poeple are willing to sacrifice their lives. The second requirement is to accomodate this larger cause to the economic forces that predominate in conditions of total anarchy."
Quote by wickedpam:
I thought it had something to do with the air pressure in the cabin that hurt there little ears that made them cry
Quote by BobR:
Oooh - McCain is doing that fundraiser with Ralph Reed right here in Atlanta!!
Of course - the protest is going to be occurring at the same time that I'm picking Raine up from the airport, so we may not be able to participate...
:kickcan:
Quote by Raine:
:coffee: Hola guten morgen!
Quote by m-hadley:Quote by Raine:
:coffee: Hola guten morgen!
Heya Raine,
Hows' the trip going? So you fly home tomorrow or today? Travel safe and hope you don't sit next to any screamin' babies :cry:
Cheers,
mfaye :hug:
Quote by Raine:I fly home monday.... Oh dear.. I think I just remembered...Quote by m-hadley:Quote by Raine:
:coffee: Hola guten morgen!
Heya Raine,
Hows' the trip going? So you fly home tomorrow or today? Travel safe and hope you don't sit next to any screamin' babies :cry:
Cheers,
mfaye :hug:
Anyone want to do the blog that morning?
Right now I am at my friends house... with Elanor (4.5) her best Friend forver, leona... and elli's little brother Luke 1.5 years... we are listening to the *Background Gang* on the cd and the girls are playing dress up... the have prcoeeded to dress up Luke and he currrently is wearing a furry Purple hat, a boa and a yellow skirt..![]()
These are awesome kids.
Quote by Raine:I fly home monday.... Oh dear.. I think I just remembered...Quote by m-hadley:Quote by Raine:
:coffee: Hola guten morgen!
Heya Raine,
Hows' the trip going? So you fly home tomorrow or today? Travel safe and hope you don't sit next to any screamin' babies :cry:
Cheers,
mfaye :hug:
Anyone want to do the blog that morning?
Right now I am at my friends house... with Elanor (4.5) her best Friend forver, leona... and elli's little brother Luke 1.5 years... we are listening to the *Background Gang* on the cd and the girls are playing dress up... the have prcoeeded to dress up Luke and he currrently is wearing a furry Purple hat, a boa and a yellow skirt..![]()
These are awesome kids.
Quote by Raine:I fly home monday.... Oh dear.. I think I just remembered...Quote by m-hadley:Quote by Raine:
:coffee: Hola guten morgen!
Heya Raine,
Hows' the trip going? So you fly home tomorrow or today? Travel safe and hope you don't sit next to any screamin' babies :cry:
Cheers,
mfaye :hug:
Anyone want to do the blog that morning?
Right now I am at my friends house... with Elanor (4.5) her best Friend forver, leona... and elli's little brother Luke 1.5 years... we are listening to the *Background Gang* on the cd and the girls are playing dress up... the have prcoeeded to dress up Luke and he currrently is wearing a furry Purple hat, a boa and a yellow skirt..![]()
These are awesome kids.
Quote by Raine:
If you can go.. you should! I can get myself back up to town babe!
Good morning loverly!
Quote by Random:
the 18th? Wasn't i doing that blog?
Quote by TriSec:
That's curious...September 11 is a Thursday this year, I wonder why the Republican convention isn't that week?
Would that be too impolitic for even them (HA!) or maybe it's just too late in the season...
Quote by Random:
the 18th? Wasn't i doing that blog?
Quote by livingonli:Quote by Random:
the 18th? Wasn't i doing that blog?
That's what I thought?
Quote by starling310:
Seriously, what would be the point of an electronic wine taster? Talk about elitist! If it tastes good to your human tongue, then who cares about what an electronic device "thinks."
![]()
Quote by BobR:Quote by TriSec:
That's curious...September 11 is a Thursday this year, I wonder why the Republican convention isn't that week?
Would that be too impolitic for even them (HA!) or maybe it's just too late in the season...
Or maybe they realize that 9/11 will make people think of Bush...
Quote by BobR:Quote by TriSec:
That's curious...September 11 is a Thursday this year, I wonder why the Republican convention isn't that week?
Would that be too impolitic for even them (HA!) or maybe it's just too late in the season...
Or maybe they realize that 9/11 will make people think of Bush...
Quote by starling310:Quote by BobR:Quote by TriSec:
That's curious...September 11 is a Thursday this year, I wonder why the Republican convention isn't that week?
Would that be too impolitic for even them (HA!) or maybe it's just too late in the season...
Or maybe they realize that 9/11 will make people think of Bush...
:spew:
So true Bobber. So very true.
They realize that 9/11 and George Bush have jumped the shark.
Quote by BobR:Quote by starling310:
Seriously, what would be the point of an electronic wine taster? Talk about elitist! If it tastes good to your human tongue, then who cares about what an electronic device "thinks."
![]()
If it costs more than $15 a bottle, it never tastes very good to me... :P
Quote by BobR:Quote by starling310:
Seriously, what would be the point of an electronic wine taster? Talk about elitist! If it tastes good to your human tongue, then who cares about what an electronic device "thinks."
![]()
If it costs more than $15 a bottle, it never tastes very good to me... :P
Quote by starling310:Quote by BobR:Quote by TriSec:
That's curious...September 11 is a Thursday this year, I wonder why the Republican convention isn't that week?
Would that be too impolitic for even them (HA!) or maybe it's just too late in the season...
Or maybe they realize that 9/11 will make people think of Bush...
:spew:
So true Bobber. So very true.
They realize that 9/11 and George Bush have jumped the shark.
Quote by starling310:
Seriously, what would be the point of an electronic wine taster? Talk about elitist! If it tastes good to your human tongue, then who cares about what an electronic device "thinks."
![]()
Quote by BobR:Quote by starling310:
Seriously, what would be the point of an electronic wine taster? Talk about elitist! If it tastes good to your human tongue, then who cares about what an electronic device "thinks."
![]()
If it costs more than $15 a bottle, it never tastes very good to me... :P
Quote by livingonli:Quote by starling310:Quote by BobR:Quote by TriSec:
That's curious...September 11 is a Thursday this year, I wonder why the Republican convention isn't that week?
Would that be too impolitic for even them (HA!) or maybe it's just too late in the season...
Or maybe they realize that 9/11 will make people think of Bush...
:spew:
So true Bobber. So very true.
They realize that 9/11 and George Bush have jumped the shark.
But the rethugs are still trying to scare people with either Iran or now Russia.
Quote by Mondobubba:
Cause umm it will be expensive, pointless and shows your cool. See Stuff White People Like # 54, Kitchen Gadgets
Quote by Mondobubba:Quote by starling310:
Seriously, what would be the point of an electronic wine taster? Talk about elitist! If it tastes good to your human tongue, then who cares about what an electronic device "thinks."
![]()
Cause umm it will be expensive, pointless and shows your cool. See Stuff White People Like # 54, Kitchen Gadgets
Quote by TriSec:Quote by Mondobubba:
Cause umm it will be expensive, pointless and shows your cool. See Stuff White People Like # 54, Kitchen Gadgets
I take offence at the Kitchen Aid comments.
I'm a baker, dammit! That's an essential item!
I have a couple of frivolous gadgets....I can usually do better with a knife and cutting board, or a cast-iron fry pan.
Quote by starling310:
Yeah, because people are judgemental pricks who think smokers are less intelligent.
Quote by Mondobubba:Quote by starling310:
Yeah, because people are judgemental pricks who think smokers are less intelligent.
Naw, just drug addicts. I keed Star, cause I love.
Quote by starling310:
: announcer guy : The Official Shampoo of Screaming Baby Airlines.
Quote by BobR:Quote by starling310:
: announcer guy : The Official Shampoo of Screaming Baby Airlines.
:spit: :rofl:
Quote by starling310:
"A hooker cut to look like Lana Turner is still a hooker."
"That is Lana Turner."
:rofl:
Quote by wickedpam:
Aw - the Lana Turner scene from LA Confidential is one of my faves
Quote by starling310:Quote by wickedpam:
Aw - the Lana Turner scene from LA Confidential is one of my faves
It's so great.
Guy Pearce is just so wonderfully persnickity.
Quote by Mondobubba:Quote by starling310:
"A hooker cut to look like Lana Turner is still a hooker."
"That is Lana Turner."
:rofl:
Well played,my favorite line from LA Confidential.
Even though the movie can't hold a candle to the awesomeness that is the novel.
Quote by starling310:
Imitation of Life is my favorite Lana Turner film...
<------ Watching Imitation of Life
Quote by starling310:Quote by wickedpam:
Aw - the Lana Turner scene from LA Confidential is one of my faves
It's so great.
Guy Pearce is just so wonderfully persnickity.
Quote by starling310:
Lindsay Graham's voice is quite possibly the world's most annoying sound.
Quote by wickedpam:
That surprises me as much as Julia Child worked for the OSS
Quote by Mondobubba:
Oh gun show this weekend at the Shrine auditorium. I can't wait! :sarcasm:
Quote by starling310:
Quote by Mondobubba:Quote by starling310:
Love it!
Quote by starling310:
There's no polite way of saying it -- and, I know, I've said it numerous times in this space -- the A380 is hideous. The 747 is one of the most elegant icons of industrial design, dignified in the fashion of a grand ocean liner. The A380 is big for the sake of big, a steroidal beluga with a malformed forehead. Is it not ironic, in a way, that it's the Europeans who have rendered something so aesthetically obnoxious. Every time I see it, I have to wonder, What were they thinking? This from the people who gave us the Concorde?
Quote by TriSec:
Now Playing: The Chillcast with Anji Bee
{mutters to self}.....oh, that's such a rut. Maybe I'll shake up the blog one day...hmm, lemme see..
Now Playing: Rammstein!![]()
Nah.....Now Playing: Toby Keith!USA! USA! USA!
Heh.....I know! Now Playing: Some old Reagan speeches! Hell, I'm voting for McCain! (urgh, that made me sick just typing it.)
Hey, watch me juggle these pots full of hot coffee! :crash: :scald:
Oh, crap, one fell in the box of Modern Jackass vintage issues! Mondo is going to kill me! Well, at least the protective outer shield is still intact. *cough* damn, coffee and argon reeks!
nothing to see here, I felt like airing out all the magazines and mopping the floor today, hmm-hmmm-hmmm-dum-de-dah-dah....
Quote by TriSec:
Hey everybody! Watch me buzz the blog!!
oh.......SHIT!
![]()
Quote by TriSec:
The Obama campaign had chartered the MD-81 from Midwest while its current campaign plane, a Boeing 757 chartered from North American Airlines, was being reconfigured. It was put into use on July 20.
The McCain campaign also debuted a new plane last month, a Boeing 737-400, chartered from Team Jet. A spokesperson, Brian Rogers, said he was unaware if the incident with the Obama plane had led to any safety evaluations of Senator McCain's campaign plane.
Quote by Mondobubba:
Raine, ya see what happens when you go away? We start to break down ala Lord of the Flies. Just today Tri has broken the no food/bev rules and crashed a plane. A fine way for a mod to behave don't you think?
Quote by Mondobubba:
Raine, ya see what happens when you go away? We start to break down ala Lord of the Flies. Just today Tri has broken the no food/bev rules and crashed a plane. A fine way for a mod to behave don't you think?
Quote by MMB:
As i recall some people have gun lovers in the family. But i guess usnnns redneck confederates love us some gun shows. Funny i have never been to one in my life. But hey people can choose the hobby they love. But no hypocrites pleaseI will penalize my own self now toodles
![]()
Quote by BobR:Quote by MMB:
As i recall some people have gun lovers in the family. But i guess usnnns redneck confederates love us some gun shows. Funny i have never been to one in my life. But hey people can choose the hobby they love. But no hypocrites pleaseI will penalize my own self now toodles
![]()
You can't choose your family. My siblings include an uber-vegan-libertarian and a republican-baptist. That doesn't make me a hypocrit for criticizing those "types". :shrug:
Quote by clintster:
So I'm catching up on my Steph Bits here and I just listened to RWW. I don't know what's scarier, the fact that Donnie in Virginia Beach's call made it on the clip, or the thought of Ernest Borgnine's 91-year old hairy palms.![]()