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Weird Science
Author: BobR    Date: 12/14/2007 13:00:33

The news out of Washington has been so aggravating and frustrating and maddening lately that - being a Friday - it's perhaps in our own best interests to take a deep breath, let it out, and try to focus on things amusing and uplifting today.

Being a bit of a science geek, I thought maybe reviewing some of the science-related stories would be just what the doctor ordered.

To start with, scientists have been able to eliminate normal fear responses in mice:
A University of Iowa study shows that loss or chemical inhibition of a protein, known as acid sensing ion channel protein (ASIC1a), reduces innate fear behavior in lab animals, making normally timid mice relatively fearless.

The findings might provide useful insight into anxiety disorders and may even point the way to a new therapeutic target.

For humans and other animals, some fears seem to be, in large part, instinctive and inborn rather than learned. For example, laboratory animals fear certain predators even though they have never been exposed to a predator. However, little is known about the brain mechanisms involved in innate fear responses.

Fortunately for the mice, other scientists have produced glow-in-the-dark cats. From this story:
South Korean scientists have cloned cats by manipulating a fluorescent protein gene, a procedure that could help develop treatments for human genetic diseases.

As part of the procedure's side effects, the cloned cats glow in the dark when exposed to ultraviolet beams.

http://www.smh.com.au/ffximage/2007/12/13/cats_wideweb__470x215,2.jpg

That should help the mice avoid the cats. However, the cats cannot lay claim to the first glow-in-the-dark "pets" - that honor would seem to go to the rabbits...

These are interesting "side-effect" stories to the real research. There have been some other good science stories that seem to have slipped under the radar. For instance: Scientists have been able to cure sickle-cell anemia in mice:
Scientists have the first evidence that those "reprogrammed stem cells" that made headlines last month really have the potential to treat disease: They used skin from the tails of sick mice to cure the rodents of sickle cell anemia....

Thursday, scientists in Alabama and Massachusetts reported a key next step when they used the technique to give mice with sickle cell anemia a healthy new blood supply....

Townes had created a strain of mice bearing the human genes for sickle cell, a devastating inherited disease of deformed red blood cells that can't carry enough oxygen.

Townes paired with prominent stem cell scientist Rudolf Jaenisch of the Whitehead Institute in Cambridge, Mass., to reprogram skin from those mice into embryonic-like stem cells. They coaxed the newly engineered cells to grow into blood-producing cells. Then they replaced the sickle cell-causing gene with a healthy version and infused the new cells.

The mice started producing healthy blood, and their sickle cell symptoms vanished.

Sure there's lots of work to be done, but it's a good start. Scientists have also been able to reverse Muscular Dystrophy:
Scientists have demonstrated that a combination of stem cell and gene therapy can be used to correct the devastating hereditary disease of muscular dystrophy, according to a new study published Wednesday.

Working with mice but using human cells, a team led by Yvan Torrente of the University of Milan, Italy showed that they could spark the most common form of the muscle-wasting disease, Duchenne muscular dystrophy (DMD), and then reverse it, offering hope to millions of sufferers world-wide.

Note that both of these cures involve the use of stem cells. If someone tries to tell you that stem cell research hasn't produced any useful results, these two studies show that is not the case.

Finally, it looks like we might be able to get some cleaner energy out of those old oil fields. The general idea is to use microbes to convert unusable oil into natural gas:
The key is the microbes, which have existed underground for hundreds of millions of years. They ferment the oil and expel natural gas without requiring oxygen.

Others have tried the approach used by Larter and his colleagues before, seeking to speed up the process by injecting more bacteria. But Larter says the key is giving the microbes their own version of vitamins.

"You'd basically feed them Miracle-Gro or fertilizer to accelerate their growth rate," he said.

The new product would be natural gas, not oil, a cleaner-burning fuel that contributes far less to global warming. Such an approach would be most promising in places with heavy oil, such as Alberta, Venezuela and Utah, other experts said.

Sure natural gas isn't as clean as solar or wind, and it's not renewable, but it could provide us a transition from oil...

So as you're fighting the shopping crowds this weekend, or sliding on wet snowy roads, just keep these stories in mind and know that there are some bright spots in our future...

 

235 comments (Latest Comment: 12/15/2007 07:49:50 by livingonli)
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Comment by velveeta jones on 12/14/2007 13:14:49
As much as I cringe hearing about animal testing I know my life has been saved and improved by it. Monkeys were used to practice brain surgery and I benefited from that when I had it. My wife was just telling me about a new drug coming out for her rare disorder that might impove her life. *sigh* Still, I hate that we need to test animals. They deserve a special place in Heaven for all their pain and suffering.



(Sorry, lost two dogs this year, so I'm a bit sensitive to animal experimentation creepiness).

Comment by velveeta jones on 12/14/2007 13:48:38
Hey, looks like Mitt has put out a response to Mikes ad (that Raine posted):





Comment by BobR on 12/14/2007 14:10:14
Hey Velveeta - just so's ya know: For the blog, put in the whole link to the YouTube video. That's different than the board where you have to pull out and use just the ID code.



I edited your comment so it was correct... ;)

Comment by livingonli on 12/14/2007 14:14:35
Good morning everyone.

Comment by livingonli on 12/14/2007 14:34:29
MGM! His lines keep making the blog.

Comment by starling310 on 12/14/2007 14:38:52
The Democrats don't talk about issues.



Oh Bill. You crack me up!



Comment by starling310 on 12/14/2007 14:39:44
BIG, expensive haircut?



How "big" we talkin Sean? Lyle lovett big? Buster Poindexter big?

Comment by livingonli on 12/14/2007 14:41:57
Good morning



How are the roads in CT today?

Comment by TriSec on 12/14/2007 14:41:59
Quote by starling310: BIG, expensive haircut?



How "big" we talkin Sean? Lyle lovett big? Buster Poindexter big?






http://a.abcnews.com/images/Entertainment/ap_big_hair12_070605_ssv.jpg


Comment by starling310 on 12/14/2007 14:43:23
Ann Coulter made a cogent point? : shudder :



Comment by starling310 on 12/14/2007 14:45:30
Quote by livingonli: Good morning



How are the roads in CT today?




They're not bad actually. Some tricky spots, but mostly clear.



Comment by starling310 on 12/14/2007 14:45:42
OMG TRI! :rofl:

Comment by Raine on 12/14/2007 14:48:52
Good Morning!

Comment by livingonli on 12/14/2007 14:49:19
Maybe Glenn Beck needs some of this.

Comment by livingonli on 12/14/2007 14:49:40
Good morning Raine. How are you today?

Comment by starling310 on 12/14/2007 14:51:25
Howdy Raine.

Comment by Raine on 12/14/2007 14:51:28
Quote by velveeta jones: Hey, looks like Mitt has put out a response to Mikes ad (that Raine posted):





:rofl:



HEya Liv, I am alright this morning... looks like you guys got quite a storm yesterday!





Comment by starling310 on 12/14/2007 14:52:39
Yay Jim!



:clap:

Comment by livingonli on 12/14/2007 14:53:33
Comment by Raine on 12/14/2007 14:53:57
Very cool blog this morning BobR... I too think that these animals deserve a special place in heaven.





b.b.b.b.buuut a GLOW IN THE DARK BUNNY??? :eep:

Comment by starling310 on 12/14/2007 14:55:53
: billy crystal : "What are we gonna do? It's already 'out there.'"

Comment by wickedpam on 12/14/2007 14:58:22
Morning! :hug:

Comment by Raine on 12/14/2007 14:58:46


OK, that is so not cool.

Comment by livingonli on 12/14/2007 15:01:06
Good morning Mala.

Comment by starling310 on 12/14/2007 15:02:10
The'Roids story still at the top of the news. :thud:

Comment by Mondobubba on 12/14/2007 15:06:38
morning fom sunny Florida.

Comment by starling310 on 12/14/2007 15:08:05
:rofl: Chris!



"I'm for Hillary. . . "



:rofl:

Comment by Raine on 12/14/2007 15:08:51
Good morning Mala and Mondo!

Comment by wickedpam on 12/14/2007 15:09:02
Hey Liv and everyone!

Comment by livingonli on 12/14/2007 15:09:17
Good morning Mondo. Think you could call Momma today.

Comment by starling310 on 12/14/2007 15:09:18
My vet's office has the "Stuff on your Cat" book!

It's awesome!



Comment by Mondobubba on 12/14/2007 15:10:11
Quote by starling310: The'Roids story still at the top of the news. :thud:




It is huge deal, I guess.

Comment by Raine on 12/14/2007 15:10:49
I missed Dan abrams... I just have a hard time with that show. HE always does a celebutard version of Keith's show, and badly at that.

Comment by Mondobubba on 12/14/2007 15:10:58
Quote by starling310: My vet's office has the "Stuff on your Cat" book!

It's awesome!







Indeed it is! :rofl:

Comment by Raine on 12/14/2007 15:11:29
Momma did pretty good, I must say.

Comment by Raine on 12/14/2007 15:12:05
Quote by Mondobubba:
Quote by starling310: My vet's office has the "Stuff on your Cat" book!

It's awesome!







Indeed it is! :rofl:


The website... it is hilarious.

Comment by Mondobubba on 12/14/2007 15:12:11
Quote by Raine: I missed Dan abrams... I just have a hard time with that show. HE always does a celebutard version of Keith's show, and badly at that.




I've got much better things to do with that hour, like watch SEASON FOUR

:modbat:



Right Bober & Raine.

Comment by wickedpam on 12/14/2007 15:13:49
Season Four of what?

Comment by livingonli on 12/14/2007 15:13:51
Quote by Raine: Momma did pretty good, I must say.


Nothing like when right-wing gasbags just shout over and beat you over the head in order to shout the talking points.

Comment by Raine on 12/14/2007 15:15:39
Huckabee took thousands in gifts...



A $1,000 pair of cufflinks from a supporter, tens of thousands of dollars of clothing from a wealthy Little Rock businessman and thousands in gift certificates and cash from staff and appointees were among the lavish gifts given to Republican presidential candidate and unexpected frontrunner Mike Huckabee while he was governor of Arkansas.



The gifts fell within Arkansas's ethics rules but have raised questions among the governor's political opponents and ethics analysts at a time when scrutiny of the candidate is intensifying, and are at odds with the humble persona Huckabee has adopted on the campaign trail.




Awww, That fits in perfect with his southern baptist preacher reputation... I wonder if he is friends with Eddie Long, and Feverand Dollar...

Comment by Mondobubba on 12/14/2007 15:15:49
Quote by wickedpam: Season Four of what?






The Wire Mala. The season five starts next month.

Comment by Raine on 12/14/2007 15:21:14
Quote by Mondobubba:
Quote by Raine: I missed Dan abrams... I just have a hard time with that show. HE always does a celebutard version of Keith's show, and badly at that.




I've got much better things to do with that hour, like watch SEASON FOUR

:modbat:



Right Bober & Raine.


We watched 2 eps last night... :D

Comment by Mondobubba on 12/14/2007 15:21:40
Haggisboarding??:spit: :rofl:

Comment by Raine on 12/14/2007 15:22:11
Quote by Raine: Huckabee took thousands in gifts...



A $1,000 pair of cufflinks from a supporter, tens of thousands of dollars of clothing from a wealthy Little Rock businessman and thousands in gift certificates and cash from staff and appointees were among the lavish gifts given to Republican presidential candidate and unexpected frontrunner Mike Huckabee while he was governor of Arkansas.



The gifts fell within Arkansas's ethics rules but have raised questions among the governor's political opponents and ethics analysts at a time when scrutiny of the candidate is intensifying, and are at odds with the humble persona Huckabee has adopted on the campaign trail.




Awww, That fits in perfect with his southern baptist preacher reputation... I wonder if he is friends with Eddie Long, and Feverand Dollar...
KEep reading the article and you will see that a certain Jennings Osbourne regularly bought Flowers for Mrs. Huckabee, and clothing for Mike... strange stuff....)



Comment by Raine on 12/14/2007 15:23:14
Quote by Mondobubba:
Quote by wickedpam: Season Four of what?






The Wire Mala. The season five starts next month.


I keep wishing it would not be the final season... :(

Comment by Mondobubba on 12/14/2007 15:23:48
Quote by Raine:
Quote by Mondobubba:
Quote by Raine: I missed Dan abrams... I just have a hard time with that show. HE always does a celebutard version of Keith's show, and badly at that.




I've got much better things to do with that hour, like watch SEASON FOUR

:modbat:



Right Bober & Raine.


We watched 2 eps last night... :D




Break out particpation ribbons!



Comment by Mondobubba on 12/14/2007 15:24:29
Quote by Raine:
Quote by Mondobubba:
Quote by wickedpam: Season Four of what?






The Wire Mala. The season five starts next month.


I keep wishing it would not be the final season... :(






Me too. :cry: :cry:

Comment by wickedpam on 12/14/2007 15:25:13
Quote by Raine:
Quote by Mondobubba:
Quote by wickedpam: Season Four of what?






The Wire Mala. The season five starts next month.


I keep wishing it would not be the final season... :(






Don't think I've ever seen it but heard ya'll talking about it.



Comment by Mondobubba on 12/14/2007 15:27:20
Quote by wickedpam:
Quote by Raine:
Quote by Mondobubba:
Quote by wickedpam: Season Four of what?






The Wire Mala. The season five starts next month.


I keep wishing it would not be the final season... :(






Don't think I've ever seen it but heard ya'll talking about it.







You have cable? You have HBO? You have on demand? hen you can catch up!

Comment by wickedpam on 12/14/2007 15:30:06
No HBO, we have Dish not cable and on Demand is not in the budget I'm afraid.