A University of Iowa study shows that loss or chemical inhibition of a protein, known as acid sensing ion channel protein (ASIC1a), reduces innate fear behavior in lab animals, making normally timid mice relatively fearless.
The findings might provide useful insight into anxiety disorders and may even point the way to a new therapeutic target.
For humans and other animals, some fears seem to be, in large part, instinctive and inborn rather than learned. For example, laboratory animals fear certain predators even though they have never been exposed to a predator. However, little is known about the brain mechanisms involved in innate fear responses.
South Korean scientists have cloned cats by manipulating a fluorescent protein gene, a procedure that could help develop treatments for human genetic diseases.
As part of the procedure's side effects, the cloned cats glow in the dark when exposed to ultraviolet beams.
Scientists have the first evidence that those "reprogrammed stem cells" that made headlines last month really have the potential to treat disease: They used skin from the tails of sick mice to cure the rodents of sickle cell anemia....
Thursday, scientists in Alabama and Massachusetts reported a key next step when they used the technique to give mice with sickle cell anemia a healthy new blood supply....
Townes had created a strain of mice bearing the human genes for sickle cell, a devastating inherited disease of deformed red blood cells that can't carry enough oxygen.
Townes paired with prominent stem cell scientist Rudolf Jaenisch of the Whitehead Institute in Cambridge, Mass., to reprogram skin from those mice into embryonic-like stem cells. They coaxed the newly engineered cells to grow into blood-producing cells. Then they replaced the sickle cell-causing gene with a healthy version and infused the new cells.
The mice started producing healthy blood, and their sickle cell symptoms vanished.
Scientists have demonstrated that a combination of stem cell and gene therapy can be used to correct the devastating hereditary disease of muscular dystrophy, according to a new study published Wednesday.
Working with mice but using human cells, a team led by Yvan Torrente of the University of Milan, Italy showed that they could spark the most common form of the muscle-wasting disease, Duchenne muscular dystrophy (DMD), and then reverse it, offering hope to millions of sufferers world-wide.
The key is the microbes, which have existed underground for hundreds of millions of years. They ferment the oil and expel natural gas without requiring oxygen.
Others have tried the approach used by Larter and his colleagues before, seeking to speed up the process by injecting more bacteria. But Larter says the key is giving the microbes their own version of vitamins.
"You'd basically feed them Miracle-Gro or fertilizer to accelerate their growth rate," he said.
The new product would be natural gas, not oil, a cleaner-burning fuel that contributes far less to global warming. Such an approach would be most promising in places with heavy oil, such as Alberta, Venezuela and Utah, other experts said.
Quote by starling310: BIG, expensive haircut?![]()
How "big" we talkin Sean? Lyle lovett big? Buster Poindexter big?
Quote by livingonli: Good morning![]()
How are the roads in CT today?
Quote by velveeta jones: Hey, looks like Mitt has put out a response to Mikes ad (that Raine posted):
Quote by starling310: The'Roids story still at the top of the news. :thud:
Quote by starling310: My vet's office has the "Stuff on your Cat" book!
It's awesome!
Quote by Mondobubba:Quote by starling310: My vet's office has the "Stuff on your Cat" book!
It's awesome!
Indeed it is! :rofl:
Quote by Raine: I missed Dan abrams... I just have a hard time with that show. HE always does a celebutard version of Keith's show, and badly at that.
Quote by Raine: Momma did pretty good, I must say.
A $1,000 pair of cufflinks from a supporter, tens of thousands of dollars of clothing from a wealthy Little Rock businessman and thousands in gift certificates and cash from staff and appointees were among the lavish gifts given to Republican presidential candidate and unexpected frontrunner Mike Huckabee while he was governor of Arkansas.
The gifts fell within Arkansas's ethics rules but have raised questions among the governor's political opponents and ethics analysts at a time when scrutiny of the candidate is intensifying, and are at odds with the humble persona Huckabee has adopted on the campaign trail.
Quote by wickedpam: Season Four of what?
Quote by Mondobubba:Quote by Raine: I missed Dan abrams... I just have a hard time with that show. HE always does a celebutard version of Keith's show, and badly at that.
I've got much better things to do with that hour, like watch SEASON FOUR
:modbat:
Right Bober & Raine.
Quote by Raine: Huckabee took thousands in gifts...
A $1,000 pair of cufflinks from a supporter, tens of thousands of dollars of clothing from a wealthy Little Rock businessman and thousands in gift certificates and cash from staff and appointees were among the lavish gifts given to Republican presidential candidate and unexpected frontrunner Mike Huckabee while he was governor of Arkansas.
The gifts fell within Arkansas's ethics rules but have raised questions among the governor's political opponents and ethics analysts at a time when scrutiny of the candidate is intensifying, and are at odds with the humble persona Huckabee has adopted on the campaign trail.
Awww, That fits in perfect with his southern baptist preacher reputation... I wonder if he is friends with Eddie Long, and Feverand Dollar...
Quote by Mondobubba:Quote by wickedpam: Season Four of what?
The Wire Mala. The season five starts next month.
Quote by Raine:Quote by Mondobubba:Quote by Raine: I missed Dan abrams... I just have a hard time with that show. HE always does a celebutard version of Keith's show, and badly at that.
I've got much better things to do with that hour, like watch SEASON FOUR
:modbat:
Right Bober & Raine.
We watched 2 eps last night... :D
Quote by Raine:Quote by Mondobubba:Quote by wickedpam: Season Four of what?
The Wire Mala. The season five starts next month.
I keep wishing it would not be the final season... :(
Quote by Raine:Quote by Mondobubba:Quote by wickedpam: Season Four of what?
The Wire Mala. The season five starts next month.
I keep wishing it would not be the final season... :(
Quote by wickedpam:Quote by Raine:Quote by Mondobubba:Quote by wickedpam: Season Four of what?
The Wire Mala. The season five starts next month.
I keep wishing it would not be the final season... :(
Don't think I've ever seen it but heard ya'll talking about it.
Quote by wickedpam: No HBO, we have Dish and I and on Demand is not in the budget I'm afraid.
Quote by Mondobubba:Quote by wickedpam: No HBO, we have Dish and I and on Demand is not in the budget I'm afraid.
There is always the video store...
Quote by wickedpam: I really don't see Edwards losing SC.
Quote by Mondobubba: :shudder: Kevin in DC.
Quote by starling310:Quote by wickedpam: I really don't see Edwards losing SC.
I see Edwards winning Iowa.
: huddles under tomato shelter :
Quote by starling310:Quote by Mondobubba: :shudder: Kevin in DC.
agreed.
:puke:
Quote by livingonli:Quote by starling310:Quote by Mondobubba: :shudder: Kevin in DC.
agreed.
:puke:
Maybe it's time for a certain caller from Jacksonville to call in who hasn't called in a while.![]()
Quote by Raine: They can now make an issue of a business mann buying flowers for Mike Huckabee... :P
Quote by livingonli:Quote by starling310:Quote by Mondobubba: :shudder: Kevin in DC.
agreed.
:puke:
Maybe it's time for a certain caller from Jacksonville to call in who hasn't called in a while.![]()
Quote by starling310: Let them talk about Edwards' hair cut. That is such an easy fight to win.
![]()
Quote by starling310: I have anecdotal evidence that I am not taken seriously because of my height.
:shrug:
Quote by wickedpam: Dupont Circle? A guy asked her out?
Quote by Mondobubba:Quote by starling310: I have anecdotal evidence that I am not taken seriously because of my height.
:shrug:
Star are you a we tiny thing? look like you fell off a charm bracelet?
Quote by starling310: Been through so much more? Seriously?
John Edwards lost a child, and his wife has Stage 4 Cancer. You think he doesn't know how to fight. Think he hasn't "been through" anything?
Come on Dude!
Quote by Raine: We need someone who can defeat the republicans. Hillary poll after poll shows that she cannot.
Quote by livingonli:Quote by wickedpam: Dupont Circle? A guy asked her out?
Was he going to kick sand in Dennis' face?
Quote by starling310: B BOX makes me want to nuzzle in her bosom.
Quote by Raine:(raine stands up and cheers) YAY STARLING!Quote by starling310: Been through so much more? Seriously?
John Edwards lost a child, and his wife has Stage 4 Cancer. You think he doesn't know how to fight. Think he hasn't "been through" anything?
Come on Dude!
Quote by starling310:Quote by Mondobubba:Quote by starling310: I have anecdotal evidence that I am not taken seriously because of my height.
:shrug:
Star are you a we tiny thing? look like you fell off a charm bracelet?
:rofl:
I'm 5'1"
![]()
Quote by Raine:I have decided that you can spoon her first,Quote by starling310: B BOX makes me want to nuzzle in her bosom.... :P
Quote by Raine: 2 more top level officials leaving WH...
Like Rats off a ship....
Quote by Mondobubba:Quote by Raine:I have decided that you can spoon her first,Quote by starling310: B BOX makes me want to nuzzle in her bosom.... :P
Oh LORDY! A B Box, Raine and Star sammich! HUBBAHUBBA! :squeezy: :creepy hetro male:
:rofl:
Quote by starling310:Quote by Mondobubba:Quote by Raine:I have decided that you can spoon her first,Quote by starling310: B BOX makes me want to nuzzle in her bosom.... :P
Oh LORDY! A B Box, Raine and Star sammich! HUBBAHUBBA! :squeezy: :creepy hetro male:
:rofl:
Well played Madam!
Quote by wickedpam:Quote by starling310:Quote by Mondobubba:Quote by starling310: I have anecdotal evidence that I am not taken seriously because of my height.
:shrug:
Star are you a we tiny thing? look like you fell off a charm bracelet?
:rofl:
I'm 5'1"
![]()
Trust me it's no fun on the taller side either at 5' 7 1/2" I usually get the you played basketball in school didn't you conversations.
Quote by Raine: So that would make me a tweener and not a Gen X-er???
Quote by Raine:It's a blunderful life!
![]()
(raine sits down next to big fluffy chair next to unclewith the LED fireplace glowing...)
Quote by Raine:I no... I was hoping that Momma would be a steroid free zone.
Quote by Raine:got his info from Fauxsnooze again??
Quote by starling310: Michael Musto puts me off a bit. . . maybe it's all my years around REALLY bitchy queens. They were all nice to me, but I hated how they treated other people.
Quote by Mondobubba:Quote by starling310: Michael Musto puts me off a bit. . . maybe it's all my years around REALLY bitchy queens. They were all nice to me, but I hated how they treated other people.
He has worn out his welcome I think. Too much time on KO.
Quote by starling310: Ashley Judd is cute, cute, cute.
And, she's does a ton of work for AIDS awareness in Africa.
:hug:
Quote by starling310:Quote by Mondobubba:Quote by starling310: Michael Musto puts me off a bit. . . maybe it's all my years around REALLY bitchy queens. They were all nice to me, but I hated how they treated other people.
He has worn out his welcome I think. Too much time on KO.
Bitchy Queens are so last season.
Quote by starling310: 17? Wow...that teeters very close to adult HOMOSEXUAL sex.
F*CKIN' FRANK!
Quote by Mondobubba:Quote by starling310: Ashley Judd is cute, cute, cute.
And, she's does a ton of work for AIDS awareness in Africa.
:hug:
Indeed! She is a wee tiny thing too! :D
Quote by starling310:Quote by Mondobubba:Quote by starling310: Ashley Judd is cute, cute, cute.
And, she's does a ton of work for AIDS awareness in Africa.
:hug:
Indeed! She is a wee tiny thing too! :D
She is. We'd be perfect together. We would double our wardrobe. One of the best things about being a Luh luh luh lesbian.
Quote by starling310:Quote by Mondobubba:Quote by starling310: Ashley Judd is cute, cute, cute.
And, she's does a ton of work for AIDS awareness in Africa.
:hug:
Indeed! She is a wee tiny thing too! :D
She is. We'd be perfect together. We would double our wardrobe. One of the best things about being a Luh luh luh lesbian.
Quote by Mondobubba:
speaking of Ashley, have you have seen Eye of the Beholder, Star? Ewan McGregor, Ms Judd & kd lang. It is a film, not a movie. For as you know a film is a movie we don't understand.
Quote by Mondobubba:Quote by starling310:Quote by Mondobubba:Quote by starling310: Ashley Judd is cute, cute, cute.
And, she's does a ton of work for AIDS awareness in Africa.
:hug:
Indeed! She is a wee tiny thing too! :D
She is. We'd be perfect together. We would double our wardrobe. One of the best things about being a Luh luh luh lesbian.
She has such nice things too. You would look fabulous!
Quote by Raine:Baracks Daddy was a tool.. From a WaPo article titled, "Ghost of a Father"
"Well, Barry," his father said. "It is a good thing to see you after so long. Very good."
For a month, the father hung around, speaking to his son's fifth-grade class, taking the boy to a Dave Brubeck concert, but never quite reestablishing himself. The trip's pivotal moment came one night as Barry prepared to watch "How the Grinch Stole Christmas," the annual Dr. Seuss special. The father said the boy had watched enough television and insisted that he go to his room to study. Barry's mother and grandparents intervened in what became a heated family argument. But they proved no match for the strong-willed father, who in an instant had reclaimed the paternal role he had long ago abdicated.
Barry went to his room, slammed the door and "began to count the days until my father would leave and things would return to normal."
=================================================
HE wouldn't let Barack watch the Grinch!!!![]()
Quote by Raine:
HE wouldn't let Barack watch the Grinch!!!![]()
Quote by Raine:Baracks Daddy was a tool.. From a WaPo article titled, "Ghost of a Father"
===============================================
"Well, Barry," his father said. "It is a good thing to see you after so long. Very good."
For a month, the father hung around, speaking to his son's fifth-grade class, taking the boy to a Dave Brubeck concert, but never quite reestablishing himself. The trip's pivotal moment came one night as Barry prepared to watch "How the Grinch Stole Christmas," the annual Dr. Seuss special. The father said the boy had watched enough television and insisted that he go to his room to study. Barry's mother and grandparents intervened in what became a heated family argument. But they proved no match for the strong-willed father, who in an instant had reclaimed the paternal role he had long ago abdicated.
Barry went to his room, slammed the door and "began to count the days until my father would leave and things would return to normal."
=================================================
HE wouldn't let Barack watch the Grinch!!!![]()
Quote by starling310: Veto. Veto. Veto.
Let me introduce to my friends.
Vito. Vito. and Vito.
:modbat:
Quote by starling310: Thom and Bernie haven't talked about Steroids! It's been 15 minutes!
:waiting:
They're talking about irrelevant issues like climate change, and budgets!
:rolleyes2:
Hello! Baseball players used Steroids guys!
Quote by starling310: Hmmm....
Do I really want to listen to Randi today?![]()
Quote by starling310: disclaimer: the underlying statement also applies to entertainers such as musicians, actors, puppeteers, and mimes.
Quote by starling310: Aw Mondo...I am sorry honey. I know Mimes are scary.
: coaxs Mondo from behind couch with a strawberry fruit roll up, chocolate milk and a coloring book :
There ya go. . . come on. . . sit on ruggie and have a snack.
Quote by wickedpam: why is randi only on Edwards case? I saw 6 candidates on that stage not one. :grumble:
Quote by starling310: Aw Mondo...I am sorry honey. I know Mimes are scary.
: coaxs Mondo from behind couch with a strawberry fruit roll up, chocolate milk and a coloring book :
There ya go. . . come on. . . sit on ruggie and have a snack.
Quote by Mondobubba:Quote by starling310: Aw Mondo...I am sorry honey. I know Mimes are scary.
: coaxs Mondo from behind couch with a strawberry fruit roll up, chocolate milk and a coloring book :
There ya go. . . come on. . . sit on ruggie and have a snack.
btw![]()
Chocolate milk and a fruit rollup???
Quote by starling310:Quote by wickedpam: why is randi only on Edwards case? I saw 6 candidates on that stage not one. :grumble:
Both are true, I think. Randi has not been my favorite lately, but she makes an interesting point; Edwards is running on a "Two Americas" platform. This would have been a nice opportunity to put his money where his mouth is.
And, Mala, you know IEdwards.
Quote by starling310:Quote by Mondobubba:Quote by starling310: Aw Mondo...I am sorry honey. I know Mimes are scary.
: coaxs Mondo from behind couch with a strawberry fruit roll up, chocolate milk and a coloring book :
There ya go. . . come on. . . sit on ruggie and have a snack.
btw![]()
Chocolate milk and a fruit rollup???
Hey! I never said I'd be a good mom.
I don't have a grasp on good snack food combinations.
Quote by Mondobubba:
Fruit rollups go with juice boxes, or boxed wine I think.
Quote by Mondobubba:
Fruit rollups go with juice boxes, or boxed wine I think.
Quote by starling310:Quote by Mondobubba:
Fruit rollups go with juice boxes, or boxed wine I think.
That wouldn't be too much fruit for a kid?
![]()
Quote by BobR:Quote by Mondobubba:
Fruit rollups go with juice boxes, or boxed wine I think.
Fruit rollups go with fruit weed to make fruit blunts...![]()
Quote by wickedpam: I don't want a Pres who'd rather head bunt someone! We have that now :cry:
Quote by starling310: Ok. In all fairness, the occasion for that drop to be relevant would be rare.
But, I think some Cartman drops are in order!
Quote by BobR:Quote by starling310: Ok. In all fairness, the occasion for that drop to be relevant would be rare.
But, I think some Cartman drops are in order!
well then I guess it's your b-b-b-birthday:
authoritie:
Quote by BobR:
IT'S FRIDAY, YA BASTAHDS!
:martini::martini:
:martini:
:martini:
:bounce::bounce:
:bounce:
:boobs2::boobs2:
:boobs2: :boobs2:
:bouncer::bouncer:
![]()
:beer::beer:
:guitar: :guitar:
:heart:
:heart:
:heart:
:heart:
:heart:
:heart:
:heart:
:boobs2: :boobs2:
:bounce::bounce:
BOUNCE!
Quote by starling310: Can I say something here? I am prepared to take the beating that ensues.
When did parents absolve themselves of the task of serving as their childrens role models? When did it become the responsibility of a man, or woman who plays a game to teach their kids the difference between what is right and acceptable and what is wrong, and unacceptable? When the news came out that Daryl Strawberry did drugs he was lambasted by the parents of America for letting their children down. Darryl didn't sign a contract to be a role model. He signed a contract to hit and catch and throw a ball. He's a human being and human beings are bound to make mistakes. Some human beings are not good human beings and will, inevitably, do bad things. Some of those bad human beings play Baseball, and Basketball, and Football, etc, etc, etc. They may excel at their sport and get paid a lucrative sum of money to do so. But, at no time did they take a test, saying that they would always be without error, or poor judgement. To the parents who use "They are a role model" as a reason why an athlete should not have faultered may I say that, perhaps, you should instill in your child the reality that these people are mere athletes. TThey entertain us. They thrill us. They make us proud sometimes. And, other times they let us down. But, at no time should they take the place of a solid role model who did sign up for that task when they became a parent.
Quote by BobR:Quote by Mondobubba:
Fruit rollups go with juice boxes, or boxed wine I think.
Fruit rollups go with fruit weed to make fruit blunts...![]()
Quote by wickedpam: have a good weekend everyone! :hug:
Quote by wickedpam: have a good weekend everyone! :hug:
Quote by livingonli: If anyone's listening to Mr. and Mrs. Kucinich on Randi, let me know how it goes.
Quote by BobR:Quote by livingonli: If anyone's listening to Mr. and Mrs. Kucinich on Randi, let me know how it goes.
Randi polished her probiscus in Dennis's butt-cleavage...![]()
Quote by livingonli:Quote by BobR:Quote by livingonli: If anyone's listening to Mr. and Mrs. Kucinich on Randi, let me know how it goes.
Randi polished her probiscus in Dennis's butt-cleavage...![]()
I really don't know if that's the mental image I wanted.![]()
![]()
Quote by livingonli: Good question. If she's out next week for surgery or vacation, and I know Christmas week is pretty much all repeats for everyone at AAR So, she could be off until after the holidays.
Hey, maybe Sam Seder will do some fill-ins.![]()
![]()
Quote by Raine: Aww Poor miss hipple... (((((((((((( :hug:)))))))))))))
Eric too... :(
And to rest of Randi's Staff. And RAndi as well, even tho you piss miss off sometimes.
Quote by Mondobubba:Quote by starling310: Ashley Judd is cute, cute, cute.
And, she's does a ton of work for AIDS awareness in Africa.
:hug:
Indeed! She is a wee tiny thing too! :D
Quote by TriSec: All right...g'nite peoples. I'll see everyone Sunday night! :slings pack over shoulder, heads to camp:
Quote by Raine:
This man claims to speak on behlf of republicans... I wonder how many people in NH will call to have him taken off thier airwaves... HE is a PIGGY :pig:
Quote by livingonli:I wonder if Mondo has theorized whether he suffers from that condition of syphilis that rots your brain like W and Bill-O apparently also suffer from?Quote by Raine: This man claims to speak on behlf of republicans... I wonder how many people in NH will call to have him taken off thier airwaves... HE is a PIGGY :pig:
Quote by Raine:NNt ot sure...Quote by livingonli:Quote by Raine:
This man claims to speak on behlf of republicans... I wonder how many people in NH will call to have him taken off thier airwaves... HE is a PIGGY :pig:
I wonder if Mondo has theorized whether he suffers from that condition of syphilis that rots your brain like W and Bill-O apparently also suffer from?but I am sure you just gave him a topic for his Thesis! :D
Quote by starling310: Anybody still up?ling. . . . drunk blogging again.
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